Evidence-Based Methadone Treatment in Toronto

The gold-standard opioid addiction treatment with decades of proven success — now available in downtown Toronto.

About Methadone

What is Methadone?

Methadone is a long-acting opioid medication specifically designed to treat opioid use disorder. It works by preventing withdrawal symptoms, reducing cravings, blocking the effects of other opioids, and providing stability with 24–36 hours of relief per dose.

Unlike short-acting opioids such as heroin, fentanyl, or oxycodone, methadone provides steady relief without the peaks and valleys that drive continued drug-seeking behavior. When taken at the correct dose, methadone prevents withdrawal and reduces cravings without causing euphoria.

How Does Methadone Work?

Methadone is a full opioid agonist, meaning it activates the same brain receptors as other opioids but in a controlled, therapeutic manner. When taken as prescribed, it:

  • Prevents withdrawal for 24–36 hours per dose
  • Does not cause euphoria at the correct therapeutic dose
  • Blocks other opioids from producing a high
  • Helps restore normal brain function disrupted by chronic opioid use
Methadone treatment pharmacy
The Process

The Methadone Treatment Process

Our structured treatment process is designed to stabilize you quickly and safely, then help you build toward lasting recovery at your own pace.

Phase 1: Initial Assessment
  • Review your opioid use history comprehensively
  • Assess current health status and medical history
  • Determine the appropriate starting methadone dose
  • Explain the treatment process and set expectations
Phase 2: Dose Stabilization (2–4 Weeks)
  • Start with a conservative initial dose for safety
  • Gradual dose increases as needed for symptom control
  • Close monitoring for sedation or inadequate dosing
  • Work toward optimal dose eliminating withdrawal and cravings
Phase 3: Maintenance Phase
  • Continue daily methadone dosing at pharmacy
  • Regular follow-up appointments with your physician
  • Periodic urine drug screens to monitor progress
  • Progressive earning of take-home doses based on stability

Earning Take-Home Doses

Initial Phase

Daily witnessed doses at pharmacy

After 2 Months (if stable)

One take-home dose per week

Progressive Earning

Additional carries every 4 weeks (up to 6 per week)

Requirements

Negative urine drug screens, compliance, and physician approval

Medical consultation
Why It Works

Benefits of Methadone Treatment

Decades of clinical research demonstrate that methadone maintenance treatment produces significant, measurable improvements across all areas of a patient's life.

Significantly reduces illicit opioid use
Dramatically decreases overdose risk and mortality
Improves overall health and quality of life
Reduces criminal activity associated with drug-seeking
Increases employment and social stability
Lowers risk of infectious diseases (HIV, Hepatitis C)
Cost-effective compared to unmanaged addiction
Recovery and wellness
Safety Information

Side Effects & Safety Information

Common Side Effects

Most side effects diminish over time and can be managed with your physician's help. Common side effects include:

Constipation
Excessive sweating
Dry mouth
Changes in sex drive
Drowsiness (initially)
Nausea and weight gain

Critical Safety Warning: Never combine methadone with alcohol, benzodiazepines, or other sedatives — this combination can be life-threatening. Always inform your physician of all medications you are taking.

Fill Your Prescription the Same Day — After your appointment, your Methadone prescription is sent electronically to the pharmacy of your choice. There is also a pharmacy in the same building if you would like to fill it the same day, making your transition into treatment seamless and stress-free.

Start Your Methadone Treatment Today

Our experienced physicians are ready to assess your needs and develop a personalized methadone treatment plan. Contact us confidentially today.

Book Assessment 647-748-1337

Need to talk to someone now? ConnexOntario is free, confidential and available 24/7 at 1-866-531-2600. If someone is in immediate danger or may be overdosing, call 911. Ontario's Good Samaritan Drug Overdose Act gives legal protection to people who call for help.

Questions

Common Questions

Yes. Physician visits for methadone treatment are covered by OHIP, so you won't be billed for doctor appointments at our Toronto clinic. The methadone itself is dispensed at the pharmacy of your choice, and most drug plans, including the Ontario Drug Benefit for eligible patients, cover the medication cost. Ask the pharmacy about your specific coverage.

Appointments at our clinic are booked in advance, so call 647-748-1337 or email info@addictionclinictoronto.ca to arrange a visit. Bring your OHIP card and a list of current medications. A referral from your family doctor can help but isn't always required; our team can advise you when you call during our 9 a.m. to 5 p.m. hours, seven days a week.

Methadone is usually taken once daily and can start easing withdrawal symptoms within a few hours, though finding the right dose takes time and regular monitoring by your doctor. Many people notice reduced cravings and withdrawal within the first one to two weeks as the dose is adjusted. Your care team will follow up closely during this early period.

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Call Now: 647-748-1337