Specialized Kadian® Treatment for Severe Opioid Addiction

A specialized second-line treatment option for patients with severe opioid use disorder who require an alternative approach.

About Kadian®

What is Kadian®?

Kadian® is a slow-release oral morphine formulation (also known as SROM – Slow Release Oral Morphine) designed specifically for treating severe opioid addiction. Unlike immediate-release morphine, Kadian® provides:

Once-Daily Dosing

Extended-release action with once-daily dosing for most patients.

Controlled Delivery

Controlled delivery over 24 hours providing therapeutic stability.

Therapeutic Stability

Steady blood levels prevent the peaks and valleys of shorter-acting opioids.

Supervised Care

Medical-grade formulation prescribed under strict physician supervision.

Second-Line Treatment: Kadian® is typically reserved for patients who have not responded adequately to first-line treatments like Suboxone® or methadone. If you haven't tried these options first, we'll discuss them at your assessment.

Patient Selection

Who is Kadian® For?

Kadian® is a specialized treatment not suitable for everyone. Our physicians carefully assess each patient to determine if Kadian® is the appropriate choice.

Ideal Candidates

Long-term, high-dose opioid use with strong physical dependence
Failed previous treatments — have not succeeded with Suboxone® or methadone
Severe withdrawal symptoms that persist despite other treatments
Complex pain and addiction — co-occurring chronic pain may be a factor
High tolerance requiring specialized medication management
Willing to comply with strict program monitoring requirements

Not Recommended For

First-time treatment seekers — should try Suboxone® or methadone first
Patients with unstable housing or lifestyle circumstances
Those unwilling to attend frequent monitoring appointments
Patients who currently use benzodiazepines (dangerous interaction)
Those unable to comply with strict program policies

Unsure if Kadian® is right for you? Contact us for a confidential assessment — our physicians will recommend the most appropriate treatment.

Requirements

Program Requirements

Due to the nature of Kadian® treatment, strict compliance is required. These requirements are in place to ensure your safety and maximize the success of your treatment.

Regular physician appointments — Initially weekly, minimum monthly thereafter
Observed medication administration — May be required at pharmacy or clinic
Urine drug screening — Frequent testing to monitor progress
Pill counts — Random or scheduled counts to prevent diversion
Stable lifestyle — Secure housing and commitment to treatment program
No benzodiazepine use — Due to dangerous interaction risks
Informed consent — Understanding and agreement to all program policies

Why These Requirements?

Kadian® is a full opioid agonist with no ceiling effect — close monitoring ensures your safety, prevents diversion, and optimizes your treatment outcomes. Our physicians provide supportive, non-judgmental oversight throughout your care.

Comparison

Kadian® vs. Methadone vs. Suboxone®

Understanding the key differences helps you and your physician make the best treatment choice for your situation.

Feature	Kadian®	Methadone	Suboxone®
Medication Type	Full agonist (SROM)	Full agonist	Partial agonist
Dosing Frequency	Once or twice daily	Once daily	Once daily
Starting Requirement	No withdrawal required	No withdrawal required	Requires mild withdrawal first
Typical Use	Second-line	First/Second-line	First-line
Take-Home Doses	Limited, strict criteria	Progressive earning	Earlier access
Monitoring Level	Very Strict	Strict	Moderate
Stabilization Speed	Variable	2–4 weeks typically	Usually within 1 week
Overdose Risk	Higher (full agonist)	Higher (full agonist)	Lower (ceiling effect)

Let our physicians guide you. The right medication depends on your individual history, health status, and treatment goals. Call us at 647-748-1337 for a confidential assessment.

Fill Your Prescription the Same Day — After your appointment, patients can have their Kadian® prescription filled immediately at our partner, Cloud Pharmacy, making your transition into treatment seamless and stress-free.

Is Kadian® Right for You?

Our experienced addiction physicians will assess your complete history and recommend the most appropriate treatment. Confidential assessments available Monday evenings.

Request Assessment 647-748-1337